The mechanical stability of proteins regulates their translocation rate into the cell nucleus

The translocation of mechanosensitive transcription factors (TFs) across the nuclear envelope is a crucial step in cellular mechanotransduction. Yet the molecular mechanisms by which external mechanical cues control the nuclear shuttling dynamics of TFs through the nuclear pore complex (NPC) to acti...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Phys
Päätekijät: Infante, Elvira, Stannard, Andrew, Board, Stephanie J., Rico-Lastres, Palma, Panagaki, Fani, Beedle, Amy E.M., Rajan, Vinoth Sundar, Rostkova, Elena, Lezamiz, Ainhoa, Wang, Yong Jian, Breen, Samuel Gulaidi, Shanahan, Catherine, Roca-Cusachs, Pere, Garcia-Manyes, Sergi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614795/
https://ncbi.nlm.nih.gov/pubmed/37484710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41567-019-0551-3
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