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The mechanical stability of proteins regulates their translocation rate into the cell nucleus

The translocation of mechanosensitive transcription factors (TFs) across the nuclear envelope is a crucial step in cellular mechanotransduction. Yet the molecular mechanisms by which external mechanical cues control the nuclear shuttling dynamics of TFs through the nuclear pore complex (NPC) to acti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Phys
मुख्य लेखकों: Infante, Elvira, Stannard, Andrew, Board, Stephanie J., Rico-Lastres, Palma, Panagaki, Fani, Beedle, Amy E.M., Rajan, Vinoth Sundar, Rostkova, Elena, Lezamiz, Ainhoa, Wang, Yong Jian, Breen, Samuel Gulaidi, Shanahan, Catherine, Roca-Cusachs, Pere, Garcia-Manyes, Sergi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614795/
https://ncbi.nlm.nih.gov/pubmed/37484710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41567-019-0551-3
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