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The mechanical stability of proteins regulates their translocation rate into the cell nucleus
The translocation of mechanosensitive transcription factors (TFs) across the nuclear envelope is a crucial step in cellular mechanotransduction. Yet the molecular mechanisms by which external mechanical cues control the nuclear shuttling dynamics of TFs through the nuclear pore complex (NPC) to acti...
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| 出版年: | Nat Phys |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614795/ https://ncbi.nlm.nih.gov/pubmed/37484710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41567-019-0551-3 |
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