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Structural snapshot of a β-arrestin-biased receptor
Atypical chemokine receptor sub-type 3 (ACKR3), a chemokine receptor, couples selectively to β-arrestins (βarrs) but not to G proteins despite having seven transmembrane (7TM) helix architecture. Yen et al. present cryogenic-electron microscopy (cryoEM) structures of agonist-bound ACKR3, elucidating...
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| Publicat a: | Trends Pharmacol Sci |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2023
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614537/ https://ncbi.nlm.nih.gov/pubmed/36057461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2022.08.005 |
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