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Terminating G-Protein Coupling: Structural Snapshots of GPCR-β-Arrestin Complexes
β-arrestins (βarrs) play multifaceted roles in the signaling and regulation of G-protein-coupled receptors (GPCRs) including their desensitization and endocytosis. Recently determined cryo-EM structures of two different GPCRs in complex with βarr1 provide the first glimpse of GPCR-βarr engagement an...
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| Yayımlandı: | Cell |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115862/ https://ncbi.nlm.nih.gov/pubmed/32169216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.02.047 |
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