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Transcriptional neighborhoods regulate transcript isoform lengths and expression levels
Sequence features of genes and their flanking regulatory regions are determinants of RNA transcript isoform expression and have been used as context-independent, plug-and-play modules in synthetic biology. However, genetic context, including the adjacent transcriptional environment, also influences...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2022
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613581/ https://ncbi.nlm.nih.gov/pubmed/35239377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg0162 |
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