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Extensive transcriptional heterogeneity revealed by isoform profiling

Transcript function is determined by sequence elements arranged on an individual RNA molecule. Variation in transcripts can affect mRNA stability, localization, and translation(2), or give rise to truncated proteins with differing subcellular localizations(3) and functions(4). Given the existence of...

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Bibliographic Details
Main Authors: Pelechano, Vicent, Wei, Wu, Steinmetz, Lars M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705217/
https://ncbi.nlm.nih.gov/pubmed/23615609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12121
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