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Genome-wide identification of transcript start and end sites by Transcript Isoform Sequencing, TIF-Seq

Hundreds of transcript isoforms with varying boundaries and alternative regulatory signals are transcribed from the genome, even in a genetically homogeneous population of cells. To study this transcriptional heterogeneity, we developed Transcript Isoform Sequencing (TIF-Seq), a method that allows t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pelechano, Vicent, Wei, Wu, Jakob, Petra, Steinmetz, Lars M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111111/
https://ncbi.nlm.nih.gov/pubmed/24967623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.121
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