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Single-cell polyadenylation site mapping reveals 3′ isoform choice variability

Cell-to-cell variability in gene expression is important for many processes in biology, including embryonic development and stem cell homeostasis. While heterogeneity of gene expression levels has been extensively studied, less attention has been paid to mRNA polyadenylation isoform choice. 3′ untra...

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Publicat a:Mol Syst Biol
Autors principals: Velten, Lars, Anders, Simon, Pekowska, Aleksandra, Järvelin, Aino I, Huber, Wolfgang, Pelechano, Vicent, Steinmetz, Lars M
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501847/
https://ncbi.nlm.nih.gov/pubmed/26040288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156198
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