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Single-cell polyadenylation site mapping reveals 3′ isoform choice variability

Cell-to-cell variability in gene expression is important for many processes in biology, including embryonic development and stem cell homeostasis. While heterogeneity of gene expression levels has been extensively studied, less attention has been paid to mRNA polyadenylation isoform choice. 3′ untra...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Syst Biol
Main Authors: Velten, Lars, Anders, Simon, Pekowska, Aleksandra, Järvelin, Aino I, Huber, Wolfgang, Pelechano, Vicent, Steinmetz, Lars M
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501847/
https://ncbi.nlm.nih.gov/pubmed/26040288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156198
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