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Widespread co-translational RNA decay reveals ribosome dynamics
It is generally assumed that mRNAs undergoing translation are protected from decay. Here we show that mRNAs are in fact co-translationally degraded. This is a widespread and conserved process affecting most genes, where 5’-3’ transcript degradation follows the last translating ribosome, producing an...
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| Publicado no: | Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461875/ https://ncbi.nlm.nih.gov/pubmed/26046441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.008 |
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