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Set3 HDAC mediates effects of overlapping non-coding transcription on gene induction kinetics

Set3 complex (Set3C) binds histone H3 dimethylated at lysine 4 (H3K4me2) to mediate deacetylation of histones in 5′ transcribed regions. To discern how Set3C affects gene expression, genome-wide transcription was analyzed in yeast undergoing a series of carbon source shifts. Deleting SET3 primarily...

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Detalhes bibliográficos
Main Authors: Kim, TaeSoo, Xu, Zhenyu, Clauder-Münster, Sandra, Steinmetz, Lars M., Buratowski, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461055/
https://ncbi.nlm.nih.gov/pubmed/22959268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.016
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