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Sample size estimation using a latent variable model for mixed outcome co‐primary, multiple primary and composite endpoints

Mixed outcome endpoints that combine multiple continuous and discrete components are often employed as primary outcome measures in clinical trials. These may be in the form of co‐primary endpoints, which conclude effectiveness overall if an effect occurs in all of the components, or multiple primary...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: McMenamin, Martina E., Barrett, Jessica K., Berglind, Anna, Wason, James M. S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612654/
https://ncbi.nlm.nih.gov/pubmed/35199380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9356
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