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A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints
It is often of interest to explore how dose affects the toxicity and efficacy properties of a novel treatment. In oncology, efficacy is often assessed through response, which is defined by a patient having no new tumour lesions and their tumour size shrinking by 30%. Usually response and toxicity ar...
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| Publicado no: | Stat Methods Med Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986906/ https://ncbi.nlm.nih.gov/pubmed/30799777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280219831038 |
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