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A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints

It is often of interest to explore how dose affects the toxicity and efficacy properties of a novel treatment. In oncology, efficacy is often assessed through response, which is defined by a patient having no new tumour lesions and their tumour size shrinking by 30%. Usually response and toxicity ar...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Stat Methods Med Res
Päätekijät: Wason, James M. S., Seaman, Shaun R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986906/
https://ncbi.nlm.nih.gov/pubmed/30799777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280219831038
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