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Employing a latent variable framework to improve efficiency in composite endpoint analysis

Composite endpoints that combine multiple outcomes on different scales are common in clinical trials, particularly in chronic conditions. In many of these cases, patients will have to cross a predefined responder threshold in each of the outcomes to be classed as a responder overall. One instance of...

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Foilsithe in:Stat Methods Med Res
Main Authors: McMenamin, Martina, Barrett, Jessica K, Berglind, Anna, Wason, James MS
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172253/
https://ncbi.nlm.nih.gov/pubmed/33234028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280220970986
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