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Employing a latent variable framework to improve efficiency in composite endpoint analysis

Composite endpoints that combine multiple outcomes on different scales are common in clinical trials, particularly in chronic conditions. In many of these cases, patients will have to cross a predefined responder threshold in each of the outcomes to be classed as a responder overall. One instance of...

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Detalles Bibliográficos
Publicado en:Stat Methods Med Res
Main Authors: McMenamin, Martina, Barrett, Jessica K, Berglind, Anna, Wason, James MS
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172253/
https://ncbi.nlm.nih.gov/pubmed/33234028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280220970986
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