Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Intestinal organoids capture essential features of the intestinal epithelium such as crypt folding, cellular compartmentalization and collective movements. Each of these processes and their coordination require patterned forces that are currently unknown. Here we map three-dimensional cellular force...

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Publicado en:Nat Cell Biol
Main Authors: Pérez-González, Carlos, Ceada, Gerardo, Greco, Francesco, Matejčić, Marija, Gómez-González, Manuel, Castro, Natalia, Menendez, Anghara, Kale, Sohan, Krndija, Denis, Clark, Andrew G., Gannavarapu, Venkata Ram, Álvarez-Varela, Adrián, Roca-Cusachs, Pere, Batlle, Eduard, Vignjevic, Danijela Matic, Arroyo, Marino, Trepat, Xavier
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611697/
https://ncbi.nlm.nih.gov/pubmed/34155382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-021-00699-6
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