Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Intestinal organoids capture essential features of the intestinal epithelium such as crypt folding, cellular compartmentalization and collective movements. Each of these processes and their coordination require patterned forces that are currently unknown. Here we map three-dimensional cellular force...

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Publicat a:Nat Cell Biol
Autors principals: Pérez-González, Carlos, Ceada, Gerardo, Greco, Francesco, Matejčić, Marija, Gómez-González, Manuel, Castro, Natalia, Menendez, Anghara, Kale, Sohan, Krndija, Denis, Clark, Andrew G., Gannavarapu, Venkata Ram, Álvarez-Varela, Adrián, Roca-Cusachs, Pere, Batlle, Eduard, Vignjevic, Danijela Matic, Arroyo, Marino, Trepat, Xavier
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611697/
https://ncbi.nlm.nih.gov/pubmed/34155382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-021-00699-6
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