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Crypt Organoid Culture as an in Vitro Model in Drug Metabolism and Cytotoxicity Studies
The gastrointestinal tract is enriched with xenobiotic processing proteins that play important roles in xenobiotic bioactivation, metabolism, and detoxification. The application of genetically modified mouse models has been instrumental in characterizing the function of xenobiotic processing genes (...
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| Publicado no: | Drug Metab Dispos |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478905/ https://ncbi.nlm.nih.gov/pubmed/28468837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075945 |
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