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Crypt Organoid Culture as an in Vitro Model in Drug Metabolism and Cytotoxicity Studies

The gastrointestinal tract is enriched with xenobiotic processing proteins that play important roles in xenobiotic bioactivation, metabolism, and detoxification. The application of genetically modified mouse models has been instrumental in characterizing the function of xenobiotic processing genes (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Metab Dispos
Prif Awduron: Lu, Wenqi, Rettenmeier, Eva, Paszek, Miles, Yueh, Mei-Fei, Tukey, Robert H., Trottier, Jocelyn, Barbier, Olivier, Chen, Shujuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478905/
https://ncbi.nlm.nih.gov/pubmed/28468837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075945
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