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Crypt Organoid Culture as an in Vitro Model in Drug Metabolism and Cytotoxicity Studies

The gastrointestinal tract is enriched with xenobiotic processing proteins that play important roles in xenobiotic bioactivation, metabolism, and detoxification. The application of genetically modified mouse models has been instrumental in characterizing the function of xenobiotic processing genes (...

詳細記述

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書誌詳細
出版年:Drug Metab Dispos
主要な著者: Lu, Wenqi, Rettenmeier, Eva, Paszek, Miles, Yueh, Mei-Fei, Tukey, Robert H., Trottier, Jocelyn, Barbier, Olivier, Chen, Shujuan
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478905/
https://ncbi.nlm.nih.gov/pubmed/28468837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075945
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