Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia

Severe neonatal hyperbilirubinemia (SNH) and the onset of bilirubin encephalopathy and kernicterus result in part from delayed expression of UDP-glucuronosyltransferase 1A1 (UGT1A1) and the inability to metabolize bilirubin. Although there is a good understanding of the early events after birth that...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Shujuan, Lu, Wenqi, Yueh, Mei-Fei, Rettenmeier, Eva, Liu, Miao, Paszek, Miles, Auwerx, Johan, Yu, Ruth T., Evans, Ronald M., Wang, Kepeng, Karin, Michael, Tukey, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338369/
https://ncbi.nlm.nih.gov/pubmed/28167773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700232114
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