Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Intestinal organoids capture essential features of the intestinal epithelium such as crypt folding, cellular compartmentalization and collective movements. Each of these processes and their coordination require patterned forces that are currently unknown. Here we map three-dimensional cellular force...

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Vydáno v:Nat Cell Biol
Hlavní autoři: Pérez-González, Carlos, Ceada, Gerardo, Greco, Francesco, Matejčić, Marija, Gómez-González, Manuel, Castro, Natalia, Menendez, Anghara, Kale, Sohan, Krndija, Denis, Clark, Andrew G., Gannavarapu, Venkata Ram, Álvarez-Varela, Adrián, Roca-Cusachs, Pere, Batlle, Eduard, Vignjevic, Danijela Matic, Arroyo, Marino, Trepat, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611697/
https://ncbi.nlm.nih.gov/pubmed/34155382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-021-00699-6
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