Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels

BACKGROUND & AIMS: Several steps in the HBV life cycle remain obscure because of a lack of robust in vitro infection models. These steps include particle entry, formation and maintenance of covalently closed circular (ccc) DNA, kinetics of gene expression and viral transmission routes. This stud...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Ko, Chunkyu, Chakraborty, Anindita, Chou, Wen-Min, Hasreiter, Julia, Wettengel, Jochen M., Stadler, Daniela, Bester, Romina, Asen, Theresa, Zhang, Ke, Wisskirchen, Karin, McKeating, Jane A., Ryu, Wang-Shick, Protzer, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611400/
https://ncbi.nlm.nih.gov/pubmed/30142426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.08.012
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