A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

Chronic hepatitis B is one of the world’s unconquered diseases with more than 240 million infected subjects at risk of developing liver disease and hepatocellular carcinoma. Hepatitis B virus reverse transcribes pre-genomic RNA to relaxed circular DNA (rcDNA) that comprises the infectious particle....

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Udgivet i:Life Sci Alliance
Main Authors: Wing, Peter AC, Davenne, Tamara, Wettengel, Jochen, Lai, Alvina G, Zhuang, Xiaodong, Chakraborty, Anindita, D’Arienzo, Valentina, Kramer, Catharina, Ko, Chunkyu, Harris, James M, Schreiner, Sabrina, Higgs, Martin, Roessler, Stephanie, Parish, Joanna L, Protzer, Ulrike, Balfe, Peter, Rehwinkel, Jan, McKeating, Jane A
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438393/
https://ncbi.nlm.nih.gov/pubmed/30918010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900355
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