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Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance
The essential role of reverse transcription in the HIV life cycle is illustrated by the fact that half of the ~30 FDA-approved drugs for HIV treatment target HIV-1 reverse transcriptase (RT). Even though more than 160 structures of RT deposited in the Protein Data Bank (PDB) have revealed the molecu...
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| Publicado no: | Curr Opin Struct Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7596924/ https://ncbi.nlm.nih.gov/pubmed/31935541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.11.011 |
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