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HIV-1 Reverse Transcriptase and Antiviral Drug Resistance (Part 1 of 2)
HIV-1 reverse transcriptase (RT) contributes to the development of resistance to all anti-AIDS drugs by introducing mutations into the viral genome. At the molecular level, mutations in RT result in resistance to RT inhibitors. Eight nucleoside/nucleotide analogs (NRTIs) and five non-nucleoside inhi...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097814/ https://ncbi.nlm.nih.gov/pubmed/23602471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2013.03.012 |
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