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HIV-1 Reverse Transcriptase and Antiviral Drug Resistance. Part 2
Structures of RT and its complexes combined with biochemical and clinical data help in illuminating the molecular mechanisms of different drug-resistance mutations. The NRTI drugs that are used in combinations have different primary mutation sites. RT mutations that confer resistance to one drug can...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097817/ https://ncbi.nlm.nih.gov/pubmed/23602470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2013.03.014 |
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