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HIV-1 Reverse Transcriptase and Antiviral Drug Resistance. Part 2

Structures of RT and its complexes combined with biochemical and clinical data help in illuminating the molecular mechanisms of different drug-resistance mutations. The NRTI drugs that are used in combinations have different primary mutation sites. RT mutations that confer resistance to one drug can...

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Bibliografske podrobnosti
Main Authors: Das, Kalyan, Arnold, Eddy
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097817/
https://ncbi.nlm.nih.gov/pubmed/23602470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2013.03.014
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