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Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase

HIV-1 Reverse Transcriptase (HIV-1 RT) has been the target of numerous approved anti-AIDS drugs that are key components of Highly Active Anti-Retroviral Therapies (HAART). It remains the target of extensive structural studies that continue unabated for almost twenty years. The crystal structures of...

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Detalhes bibliográficos
Main Authors: Singh, Kamalendra, Marchand, Bruno, Kirby, Karen A., Michailidis, Eleftherios, Sarafianos, Stefan G.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850067/
https://ncbi.nlm.nih.gov/pubmed/20376302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2020606
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