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Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase

HIV-1 Reverse Transcriptase (HIV-1 RT) has been the target of numerous approved anti-AIDS drugs that are key components of Highly Active Anti-Retroviral Therapies (HAART). It remains the target of extensive structural studies that continue unabated for almost twenty years. The crystal structures of...

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Main Authors: Singh, Kamalendra, Marchand, Bruno, Kirby, Karen A., Michailidis, Eleftherios, Sarafianos, Stefan G.
格式: Artigo
語言:Inglês
出版: Molecular Diversity Preservation International (MDPI) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850067/
https://ncbi.nlm.nih.gov/pubmed/20376302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2020606
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