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Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening
Type II DNA topoisomerases (topo II) flip the spatial positions of two DNA duplexes, called G- and T- segments, by a cleavage-passage-resealing mechanism. In living cells, these DNA segments can be derived from distant sites on the same chromosome. Due to lack of proper methodology, however, no dire...
Zapisane w:
| Wydane w: | Sci Rep |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7596052/ https://ncbi.nlm.nih.gov/pubmed/33122676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75004-w |
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