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Topoisomerase IIβ Activates a Subset of Neuronal Genes that Are Repressed in AT-Rich Genomic Environment

DNA topoisomerase II (topo II) catalyzes a strand passage reaction in that one duplex is passed through a transient brake or gate in another. Completion of late stages of neuronal development depends on the presence of active β isoform (topo IIβ). The enzyme appears to aid the transcriptional induct...

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Hlavní autoři: Sano, Kuniaki, Miyaji-Yamaguchi, Mary, Tsutsui, Kimiko M., Tsutsui, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605559/
https://ncbi.nlm.nih.gov/pubmed/19116664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004103
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