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The function of DNA topoisomerase IIβ in neuronal development

Type II DNA topoisomerases (Tops) are ATP-dependent enzymes that catalyze topological transformations of genomic DNA by the transport of one DNA double helix through another. In mammals, there are 2 isoforms of DNA Top II, termed Top IIα and Top IIβ. The IIβ isoform is abundantly expressed in cells...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Heng, Xin, Le, Wei-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560355/
https://ncbi.nlm.nih.gov/pubmed/20882068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-0625-9
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