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Role of Topoisomerase IIβ in DNA Damage Response following IR and Etoposide
The role of topoisomerase IIβ was investigated in cell lines exposed to two DNA damaging agents, ionising radiation (IR) or etoposide, a drug which acts on topoisomerase II. The appearance and resolution of γH2AX foci in murine embryonic fibroblast cell lines, wild type and null for DNA topoisomeras...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE-Hindawi Access to Research
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935090/ https://ncbi.nlm.nih.gov/pubmed/20847952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/710589 |
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