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Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin
The genome is organized into large scale structures in the interphase nucleus. Pericentromeric heterochromatin represents one such compartment characterized by histones H3 and H4 tri-methylated at K9 and K20 respectively and with a correspondingly low level of histone acetylation. HP1 proteins are c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104810/ https://ncbi.nlm.nih.gov/pubmed/21647300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.1.14194 |
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