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Genomic Regions Targeted by DNA Topoisomerase IIβ Frequently Interact With a Nuclear Scaffold/Matrix Protein hnRNP U/SAF‐A/SP120

Type II DNA topoisomerases (topo II) play critical roles in some cellular events through repeated cleavage/rejoining of nuclear DNA. The β isoform (topo IIβ) is essential for the transcriptional induction of neuronal genes in terminal differentiation. Genomic sites targeted by the enzyme are nonrand...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Miyaji, Mary, Furuta, Ryohei, Sano, Kuniaki, Tsutsui, Kimiko M., Tsutsui, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024068/
https://ncbi.nlm.nih.gov/pubmed/25418483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25024
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