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Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain
Lens epithelium-derived growth factor (LEDGF) or p75 is a co-activator of general transcription and also involved in insertion of human immunodeficiency virus type I (HIV-1) cDNA into host cell genome, which occurs preferentially to active transcription units. These phenomena may share an underlying...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130267/ https://ncbi.nlm.nih.gov/pubmed/21345933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr088 |
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