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Toward Drug-Like Multispecific Antibodies by Design

The success of antibody therapeutics is strongly influenced by their multifunctional nature that couples antigen recognition mediated by their variable regions with effector functions and half-life extension mediated by a subset of their constant regions. Nevertheless, the monospecific IgG format is...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sawant, Manali S., Streu, Craig N., Wu, Lina, Tessier, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589779/
https://ncbi.nlm.nih.gov/pubmed/33053650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207496
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