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Selecting and engineering monoclonal antibodies with drug-like specificity

Despite the recent explosion in the use of monoclonal antibodies (mAbs) as drugs, it remains a significant challenge to generate antibodies with a combination of physicochemical properties that are optimal for therapeutic applications. We argue that one of the most important and underappreciated dru...

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Publicat a:Curr Opin Biotechnol
Autors principals: Starr, Charles G., Tessier, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829062/
https://ncbi.nlm.nih.gov/pubmed/30822699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.01.008
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