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Selecting and engineering monoclonal antibodies with drug-like specificity
Despite the recent explosion in the use of monoclonal antibodies (mAbs) as drugs, it remains a significant challenge to generate antibodies with a combination of physicochemical properties that are optimal for therapeutic applications. We argue that one of the most important and underappreciated dru...
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| Udgivet i: | Curr Opin Biotechnol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829062/ https://ncbi.nlm.nih.gov/pubmed/30822699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.01.008 |
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