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Toward Drug-Like Multispecific Antibodies by Design

The success of antibody therapeutics is strongly influenced by their multifunctional nature that couples antigen recognition mediated by their variable regions with effector functions and half-life extension mediated by a subset of their constant regions. Nevertheless, the monospecific IgG format is...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Sawant, Manali S., Streu, Craig N., Wu, Lina, Tessier, Peter M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589779/
https://ncbi.nlm.nih.gov/pubmed/33053650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207496
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