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Toward Drug-Like Multispecific Antibodies by Design
The success of antibody therapeutics is strongly influenced by their multifunctional nature that couples antigen recognition mediated by their variable regions with effector functions and half-life extension mediated by a subset of their constant regions. Nevertheless, the monospecific IgG format is...
Guardat en:
| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7589779/ https://ncbi.nlm.nih.gov/pubmed/33053650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207496 |
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