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Advances in Antibody Design
The use of monoclonal antibodies as therapeutics requires optimizing several of their key attributes. These include binding affinity and specificity, folding stability, solubility, pharmacokinetics, effector functions, and compatibility with the attachment of additional antibody domains (bispecific...
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| Publicado no: | Annu Rev Biomed Eng |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289076/ https://ncbi.nlm.nih.gov/pubmed/26274600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-bioeng-071114-040733 |
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