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Advances in Antibody Design
The use of monoclonal antibodies as therapeutics requires optimizing several of their key attributes. These include binding affinity and specificity, folding stability, solubility, pharmacokinetics, effector functions, and compatibility with the attachment of additional antibody domains (bispecific...
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| 出版年: | Annu Rev Biomed Eng |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289076/ https://ncbi.nlm.nih.gov/pubmed/26274600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-bioeng-071114-040733 |
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