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Myocardial Phosphodiesterases and their Role in cGMP Regulation
Cyclic nucleotide phosphodiesterases comprise an 11-member superfamily yielding near 100 isoform variants that hydrolyze cAMP or cGMP to their respective 5’-monophosphate form. Each plays a role in compartmentalized cyclic nucleotide signaling, with varying selectivity for each substrate, and convey...
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| 發表在: | J Cardiovasc Pharmacol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7585454/ https://ncbi.nlm.nih.gov/pubmed/31651671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000773 |
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