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Role of cGMP Signaling and Phosphodiesterase-5 inhibitors in Cardioprotection

cGMP is an important intracellular second messenger that mediates multiple tissue and cellular responses. The cGMP pathway is a key element in the pathophysiology of the heart and its modulation by drugs such as phosphodiesterase-5 (PDE-5) inhibitors and guanylate cyclase activators may represent a...

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Bibliografiske detaljer
Udgivet i:J Am Coll Cardiol
Main Authors: Kukreja, Rakesh C., Salloum, Fadi N., Das, Anindita
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230443/
https://ncbi.nlm.nih.gov/pubmed/22624832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.09.086
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