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Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases
Phosphodiesterase type-5 (PDE-5) is an enzyme that catalyzes the hydrolytic degradation of cyclic GMP – an essential intracellular second messenger that modulates diverse biological processes in living cells. Three selective inhibitors of PDE-5 – sildenafil, vardenafil and tadalafil – have been succ...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Pulsus Group Inc
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206106/ https://ncbi.nlm.nih.gov/pubmed/22131856 |
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