Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases

Phosphodiesterase type-5 (PDE-5) is an enzyme that catalyzes the hydrolytic degradation of cyclic GMP – an essential intracellular second messenger that modulates diverse biological processes in living cells. Three selective inhibitors of PDE-5 – sildenafil, vardenafil and tadalafil – have been succ...

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Bibliografiske detaljer
Main Authors: Kukreja, Rakesh C, Salloum, Fadi N, Das, Anindita, Koka, Saisudha, Ockaili, Ramzi A, Xi, Lei
Format: Artigo
Sprog:Inglês
Udgivet: Pulsus Group Inc 2011
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206106/
https://ncbi.nlm.nih.gov/pubmed/22131856
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