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Myocardial Phosphodiesterases and their Role in cGMP Regulation

Cyclic nucleotide phosphodiesterases comprise an 11-member superfamily yielding near 100 isoform variants that hydrolyze cAMP or cGMP to their respective 5’-monophosphate form. Each plays a role in compartmentalized cyclic nucleotide signaling, with varying selectivity for each substrate, and convey...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Dunkerly-Eyring, Brittany, Kass, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585454/
https://ncbi.nlm.nih.gov/pubmed/31651671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000773
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