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A novel role for a Drosophila homologue of cGMP-specific phosphodiesterase in the active transport of cGMP
cGMP was first discovered in urine, demonstrating that kidney cells extrude this cyclic nucleotide. Drosophila Malpighian tubules provide a model renal system in which a homologue of mammalian PDE (phosphodiesterase) 6 is expressed. In humans, this cG-PDE (cGMP-specific PDE) is specifically expresse...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360698/ https://ncbi.nlm.nih.gov/pubmed/16232123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051505 |
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