Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation.

Míreanna Comhchosúla

• cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
  le: Francis, Sharron H., et al.
  Foilsithe: (2010)
• Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension
  le: Murray, Fiona, et al.
  Foilsithe: (2002)
• cGMP-dependent protein kinase protects cGMP from hydrolysis by phosphodiesterase-5.
  le: Kotera, Jun, et al.
  Foilsithe: (2003)
• Individual Cerebellar Purkinje Cells Express Different cGMP Phosphodiesterases (PDEs): In Vivo Phosphorylation of cGMP-Specific PDE (PDE5) as an Indicator of cGMP-dependent protein kinase (PKG) Activation
  le: Shimizu-Albergine, Masami, et al.
  Foilsithe: (2003)
• Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases.
  le: Charbonneau, H, et al.
  Foilsithe: (1990)